Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865541:139865568:[+] chr22:51160147:51160166:[+] nonBSJ supported CDS

circRNA 5':UCCAG-UCUUCCAGCAAUUACUGGUCUUC 3'


            |||| ||:||| |||||||:


target  3':CGGUCGAGGAGG--------GACCAGAG 5'

 -23.50 1 RIC-seq
chrX:139865541:139865569:[+] chr22:51160146:51160166:[+] nonBSJ supported CDS

circRNA 5':UCCAG-UCUUCCAGCAAUUACUGGUCUUCC 3'


            |||| ||:||| |||||||:|


target  3':CGGUCGAGGAGG--------GACCAGAGG 5'

 -26.20 15 RIC-seq
chrX:139865903:139865953:[+] chr22:51159583:51159640:[+] nonBSJ supported CDS

circRNA 5': CCGGAAAAAAUCC----AGGUC----------UUC---CAGCCAAUAUAUGUCUUCCUGAAGAUCCAC 3'


            |||| || |||:| :|| |||||| ||| |||


target  3':UGGCCCUCCCGCGGACCCUCCGGUCUCGAGCGAGAGCCCGUCGGUCCCG-----------UUCCCGGUC 5'

 -19.60 1 RIC-seq
chrX:139865913:139865946:[+] chr22:51159576:51159620:[+] nonBSJ supported CDS

circRNA 5':UCCAGG------UCUUC--CAGCCAA--UAUAUGUCUUCC-UGAA 3'


            ||||: |||: |||||| :| |:| |||


target  3':CGGUCUCGAGCGAGAGCCCGUCGGUCCCGUUCCCGGUCCCCACUC 5'

 -16.90 24 RIC-seq
chrX:139865913:139865946:[+] chr22:51159577:51159620:[+] nonBSJ supported CDS

circRNA 5':UCCAGG------UCUUC--CAGCCAA--UAUAUGUCUUCC-UGAA 3'


            ||||: |||: |||||| :| |:| |||


target  3':CGGUCUCGAGCGAGAGCCCGUCGGUCCCGUUCCCGGUCCCCACU 5'

 -16.70 1 RIC-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr22:51159576:51159620:[+] target 2442348 chr22:51159604-51159605 C>T Phelan-McDermid_syndrome ClinVar
chr22:51159576:51159620:[+] target 30560 chr22:51159610-51159611 C>T Intellectual_disability|Schizophrenia_15 ClinVar
chr22:51159577:51159620:[+] target 2442348 chr22:51159604-51159605 C>T Phelan-McDermid_syndrome ClinVar
chr22:51159577:51159620:[+] target 30560 chr22:51159610-51159611 C>T Intellectual_disability|Schizophrenia_15 ClinVar
chr22:51159583:51159640:[+] target 2442348 chr22:51159604-51159605 C>T Phelan-McDermid_syndrome ClinVar
chr22:51159583:51159640:[+] target 30560 chr22:51159610-51159611 C>T Intellectual_disability|Schizophrenia_15 ClinVar
chr22:51159583:51159640:[+] target 978893 chr22:51159630-51159631 GC>G Intellectual_disability ClinVar
chr22:51159583:51159640:[+] target - chr22:51159630-51159631 G>T LICA-CN ICGC