Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865372:139865396:[+] chr2:5834476:5834502:[+] nonBSJ supported 3UTR

circRNA 5':AACAACUCCGGGUCUUCCA--GCGACU 3'


            ||||||||:|: || ||:|||


target  3':GUGUUGAGGUCU-GAUCCAUACGUUGAU 5'

 -23.80 2 RIC-seq
chrX:139865577:139865595:[+] chr2:5834424:5834444:[+] nonBSJ supported 3UTR

circRNA 5':CCAGAUCUUC--CAGGAAAAU 3'


            ||:| ||||||||


target  3':UGUUUUUUUCCUGUCCUUUUU 5'

 -9.80 2 RIC-seq
chrX:139865636:139865665:[+] chr2:5835718:5835767:[+] nonBSJ supported 3UTR

circRNA 5':GGUC--UUCCA------------------UCAA-AUACAGAUCUUCCAGCU 3'


            ||| ||||| |||| ||||||| ||||||||


target  3':AUAGUCAAGGUCGACUAAAUAAUUUUAACAGUUCUAUGUCU-GAAGGUCGU 5'

 -28.80 1 RIC-seq
chrX:139865801:139865853:[+] chr2:5839388:5839449:[+] nonBSJ supported 3UTR

circRNA 5':AGUGUCUUCCAGAA------AGAA--AUCC-----AGGUCUUCCAGUCAGUCAGUGUCUUCCAGAA 3'


            | |:|:| |||| |||| |||| |::|||||| | | ||| | ||||


target  3':AC-CGGGAA-UCUUAUUGACUCUUUAUAGGACUUUUUUAGAAGGGA---CUUUGACAUUAUUUCUUU 5'

 -19.40 2 RIC-seq
chrX:139866333:139866374:[+] chr2:5835521:5835578:[+] nonBSJ supported 3UTR

circRNA 5':GGUCUUCCA---------------GGAAAUCCGUGUCUUCCAG---CAAAUCCA-CGUCUU 3'


            |:||| ::|||| || ||||| ||||:| |:|||


target  3':ACGGAAAAAAAAAAGAAAAAACGAUUUUUA-GCUCUU-AGGUCAAAGUUUGGAAGGUAGA 5'

 -18.80 1 RIC-seq
chrX:139866333:139866378:[+] chr2:5835512:5835578:[+] nonBSJ supported 3UTR

circRNA 5':GGUCUUCCA---------------GGAAAUCCGUGUCUUCCAG---CAAAUCCA-CGUCU-----UCCAA 3'


            |:||| ::|||| || ||||| ||||:| |:||| :|||


target  3':ACGGAAAAAAAAAAGAAAAAACGAUUUUUA-GCUCUU-AGGUCAAAGUUUGGAAGGUAGACCCCGGGGU 5'

 -21.40 1 RIC-seq
chrX:139866688:139866704:[+] chr2:5835754:5835770:[+] nonBSJ supported 3UTR

circRNA 5':CUCUGUGUCUUCCAGCA 3'


            |||:| |||||||


target  3':AAGAUAGUCAAGGUCGA 5'

 -16.60 2 RIC-seq
chrX:139866052:139866088:[+] chr2:5833151:5833187:[+] nonBSJ supported CDS

circRNA 5': GGAUAA---UUUGGGUCUUC-CUGAAAAUCUACGUCUUCCA 3'


            || :|||:|:| |:| || ||:||:||


target  3':GCCGGUACACGAACUCGGCGUCGGC-----GAGGCGGAGGGC 5'

 -21.60 2 RIC-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr2:5833151:5833187:[+] target 3251955 chr2:5833152-5833153 G>A Hypogonadotropic_hypogonadism ClinVar
chr2:5833151:5833187:[+] target 420675 chr2:5833152-5833153 G>C Intellectual_developmental_disorder_with_microcephaly_and_with_or_without_ocular_malformations_or_hypogonadotropic_hypogonadism|not_provided ClinVar
chr2:5833151:5833187:[+] target 870388 chr2:5833158-5833159 C>T Intellectual_developmental_disorder_with_microcephaly_and_with_or_without_ocular_malformations_or_hypogonadotropic_hypogonadism ClinVar
chr2:5833151:5833187:[+] target 2443020 chr2:5833170-5833171 G>C Intellectual_developmental_disorder_with_microcephaly_and_with_or_without_ocular_malformations_or_hypogonadotropic_hypogonadism ClinVar
chr2:5833151:5833187:[+] target 620069 chr2:5833175-5833176 A>G Intellectual_developmental_disorder_with_microcephaly_and_with_or_without_ocular_malformations_or_hypogonadotropic_hypogonadism ClinVar
chr2:5833151:5833187:[+] target 2443021 chr2:5833179-5833180 A>C Intellectual_developmental_disorder_with_microcephaly_and_with_or_without_ocular_malformations_or_hypogonadotropic_hypogonadism ClinVar
chr2:5833151:5833187:[+] target - chr2:5833187-5833188 G>A COCA-CN ICGC
chr2:5835512:5835578:[+] target - chr2:5835517-5835518 C>A PRAD-CA ICGC
chr2:5839388:5839449:[+] target - chr2:5839413-5839414 A>T PACA-CA ICGC