Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865361:139865394:[+] chr2:166848490:166848520:[-] nonBSJ supported CDS

circRNA 5':CAAGGUC-UUCCAACAACUCCGGGUCUUCCAGCGA 3'


            |||: |||||||| |||| |:||| |


target  3':UUUCUUUUAAGGUUGUCUA--CCCA-AGGGUGUC 5'

 -21.40 1 RIC-seq
chrX:139865361:139865408:[+] chr2:166848490:166848527:[-] nonBSJ supported CDS

circRNA 5':CAAGGUC-UUCCAACAACUCCGGGUCUUCCAGCGACUUCAAGUCUUCCA 3'


            |||: |||||||| |||| |:||| | |||||:||


target  3':UUUCUUUUAAGGUUGUCUA--CCCA-AGGGU-G-------UCAGAGGGA 5'

 -30.30 56 RIC-seq
chrX:139865362:139865408:[+] chr2:166848490:166848527:[-] nonBSJ supported CDS

circRNA 5': AAGGUC-UUCCAACAACUCCGGGUCUUCCAGCGACUUCAAGUCUUCCA 3'


            |||: |||||||| |||| |:||| | |||||:||


target  3':UUUCUUUUAAGGUUGUCUA--CCCA-AGGGU-G-------UCAGAGGGA 5'

 -29.80 1 RIC-seq
chrX:139865527:139865554:[+] chr2:166859098:166859125:[-] nonBSJ supported CDS

circRNA 5':AGUCUUCCAG--CAAAUCCAGUCUUCCAGC 3'


            |||||| |||| || ||| ||||


target  3':GCAGAAGCUACAGUUU-GGACAGU-GGUCA 5'

 -21.00 6 RIC-seq
chrX:139866636:139866662:[+] chr2:166908472:166908501:[-] nonBSJ supported CDS

circRNA 5':CCAGGGCUUCCAGCAUCUG---CUCGUCUU 3'


            |||||||:||| | |:||


target  3':AGUCCCGAGGGUGUUACCAAAAGUCCGGAC 5'

 -23.70 2 RIC-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr2:166848490:166848520:[-] target 1705492 chr2:166848491-166848492 A>G Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848520:[-] target 963219 chr2:166848492-166848493 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts|Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848520:[-] target 189983 chr2:166848493-166848494 G>GAAAATTCC Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848520:[-] target 663520 chr2:166848496-166848497 AA>CAGATGGG Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848520:[-] target 68567 chr2:166848500-166848501 C>T Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848520:[-] target 2726761 chr2:166848502-166848503 AAC>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848520:[-] target 373148 chr2:166848503-166848504 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts|not_provided ClinVar
chr2:166848490:166848520:[-] target 530478 chr2:166848516-166848517 C>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848520:[-] target 1457986 chr2:166848516-166848517 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848520:[-] target 578647 chr2:166848518-166848519 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848520:[-] target 2753511 chr2:166848519-166848520 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 1705492 chr2:166848491-166848492 A>G Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848527:[-] target 963219 chr2:166848492-166848493 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts|Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848527:[-] target 189983 chr2:166848493-166848494 G>GAAAATTCC Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848527:[-] target 663520 chr2:166848496-166848497 AA>CAGATGGG Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 68567 chr2:166848500-166848501 C>T Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848527:[-] target 2726761 chr2:166848502-166848503 AAC>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 373148 chr2:166848503-166848504 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts|not_provided ClinVar
chr2:166848490:166848527:[-] target 530478 chr2:166848516-166848517 C>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 1457986 chr2:166848516-166848517 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 578647 chr2:166848518-166848519 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 2753511 chr2:166848519-166848520 A>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 189876 chr2:166848521-166848522 T>C Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166848490:166848527:[-] target 530440 chr2:166848522-166848523 C>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 3634003 chr2:166848522-166848523 C>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 2862362 chr2:166848524-166848525 C>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166848490:166848527:[-] target 801789 chr2:166848524-166848525 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts|Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166859098:166859125:[-] target 2734302 chr2:166859098-166859099 C>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166859098:166859125:[-] target 190014 chr2:166859098-166859099 C>G Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166859098:166859125:[-] target 68537 chr2:166859098-166859099 C>T Early_infantile_epileptic_encephalopathy_with_suppression_bursts|Severe_myoclonic_epilepsy_in_infancy|not_provided|Inborn_genetic_diseases ClinVar
chr2:166859098:166859125:[-] target 2127501 chr2:166859112-166859113 AACCTGTCACC>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166859098:166859125:[-] target 1738288 chr2:166859112-166859113 A>C Inborn_genetic_diseases ClinVar
chr2:166859098:166859125:[-] target 801796 chr2:166859119-166859120 CA>C Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166908472:166908501:[-] target 212120 chr2:166908474-166908475 A>G Seizure ClinVar
chr2:166908472:166908501:[-] target 68581 chr2:166908477-166908478 G>A Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166908472:166908501:[-] target 940560 chr2:166908477-166908478 G>C Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 1686158 chr2:166908477-166908478 G>T Generalized_epilepsy_with_febrile_seizures_plus,_type_2 ClinVar
chr2:166908472:166908501:[-] target 68580 chr2:166908478-166908479 C>T Severe_myoclonic_epilepsy_in_infancy|Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 646877 chr2:166908480-166908481 C>A Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 2828920 chr2:166908484-166908485 CA>C Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 2101470 chr2:166908484-166908485 C>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 2845704 chr2:166908489-166908490 GT>G Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 2016244 chr2:166908490-166908491 T>C Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar
chr2:166908472:166908501:[-] target 801818 chr2:166908497-166908498 GC>G SCN1A_Seizure_Disorders|Severe_myoclonic_epilepsy_in_infancy ClinVar
chr2:166908472:166908501:[-] target 1066324 chr2:166908500-166908501 T>C Early_infantile_epileptic_encephalopathy_with_suppression_bursts ClinVar