Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865445:139865481:[+] chr21:33036101:33036136:[+] nonBSJ supported CDS

circRNA 5':AGAAAAUCCACAUCUUCCAGACAAUCCAUGUC-UUCCG 3'


            | :|||||:|||| ||||| | ||||


target  3':ACGAAGGGGUGUGGAAGUGACC--AGGUAAUGAAAGGA 5'

 -26.20 3 RIC-seq
chrX:139866311:139866322:[+] chr21:33039607:33039618:[+] nonBSJ supported CDS

circRNA 5':UCCAUAGCUUCC 3'


            |||:| | ||


target  3':CGGUGUGGUAGA 5'

 -8.20 24 RIC-seq
chrX:139866407:139866429:[+] chr21:33040834:33040855:[+] nonBSJ supported CDS

circRNA 5':UCUUCCAGCCUACUUGUGUCUUC 3'


            |||||||| |: ||||||


target  3':UGAAGGUCGCAA-AGGACAGAAA 5'

 -21.40 1 RIC-seq
chrX:139866692:139866742:[+] chr21:33039600:33039649:[+] nonBSJ supported CDS

circRNA 5':GUGUCUUC-CAGCAUCUUCAUGUCUUCCAACAACUAC-CCAGUCUUCCAUCAA 3'


            || || ||| ||||||| || | |:|| ||| |||| |||


target  3': ACUCUAGUGUCUUAGAAGUUAUCUGUGUAGCCGGUGUGGU-AGAAAC-AGUC 5'

 -22.40 22 RIC-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr21:33036101:33036136:[+] target 873196 chr21:33036125-33036126 T>C Spastic_tetraplegia_and_axial_hypotonia,_progressive|not_provided|Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 14766 chr21:33039603-33039604 A>C Amyotrophic_lateral_sclerosis_type_1|Amyotrophic_lateral_sclerosis_1,_autosomal_recessive|SOD1-related_disorder|Amyotrophic_lateral_sclerosis|not_provided ClinVar
chr21:33039600:33039649:[+] target 1802147 chr21:33039603-33039604 A>T Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 3778878 chr21:33039609-33039610 A>ATGG Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 2634277 chr21:33039611-33039612 G>A Amyotrophic_lateral_sclerosis_type_1|SOD1-related_disorder ClinVar
chr21:33039600:33039649:[+] target 14784 chr21:33039611-33039612 G>C Amyotrophic_lateral_sclerosis_type_1|Motor_neuron_disease ClinVar
chr21:33039600:33039649:[+] target 14759 chr21:33039611-33039612 G>T Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 1072003 chr21:33039612-33039613 G>A Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 14760 chr21:33039612-33039613 G>C Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 2197104 chr21:33039617-33039618 G>A Amyotrophic_lateral_sclerosis_type_1|not_provided ClinVar
chr21:33039600:33039649:[+] target 692200 chr21:33039621-33039622 A>T Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 14761 chr21:33039633-33039634 A>G Amyotrophic_lateral_sclerosis_type_1|not_provided|Motor_neuron_disease ClinVar
chr21:33039600:33039649:[+] target 2736984 chr21:33039635-33039636 G>A Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 1066874 chr21:33039635-33039636 G>C Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039600:33039649:[+] target 14767 chr21:33039644-33039645 A>T Abnormal_central_motor_function|Amyotrophic_lateral_sclerosis_1,_autosomal_recessive ClinVar
chr21:33039600:33039649:[+] target 695024 chr21:33039648-33039649 C>T Amyotrophic_lateral_sclerosis|Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039607:33039618:[+] target 3778878 chr21:33039609-33039610 A>ATGG Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039607:33039618:[+] target 2634277 chr21:33039611-33039612 G>A Amyotrophic_lateral_sclerosis_type_1|SOD1-related_disorder ClinVar
chr21:33039607:33039618:[+] target 14784 chr21:33039611-33039612 G>C Amyotrophic_lateral_sclerosis_type_1|Motor_neuron_disease ClinVar
chr21:33039607:33039618:[+] target 14759 chr21:33039611-33039612 G>T Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039607:33039618:[+] target 1072003 chr21:33039612-33039613 G>A Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039607:33039618:[+] target 14760 chr21:33039612-33039613 G>C Amyotrophic_lateral_sclerosis_type_1 ClinVar
chr21:33039607:33039618:[+] target 2197104 chr21:33039617-33039618 G>A Amyotrophic_lateral_sclerosis_type_1|not_provided ClinVar
chr21:33040834:33040855:[+] target 873202 chr21:33040838-33040839 A>G Amyotrophic_lateral_sclerosis_type_1|not_provided ClinVar
chr21:33040834:33040855:[+] target 1163753 chr21:33040839-33040840 C>T Amyotrophic_lateral_sclerosis_type_1|not_provided ClinVar
chr21:33040834:33040855:[+] target 586635 chr21:33040846-33040847 C>A Amyotrophic_lateral_sclerosis_type_1|not_provided ClinVar
chr21:33040834:33040855:[+] target 2000951 chr21:33040851-33040852 G>T Amyotrophic_lateral_sclerosis_type_1 ClinVar
chrX:139866311:139866322:[+] circRNA - chrX:139866318-139866319 C>T BTCA-JP ICGC