Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865552:139865576:[+] chr22:22114233:22114272:[-] nonBSJ supported 3UTR

circRNA 5': AGCAAUUACUG---GUCUUCC----------ACCAAAU 3'


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target  3':UUCAGUAAUGUAUUACGGGUUAUAACUAUUCUUGGUUUAC 5'

 -9.40 2 RIC-seq
chrX:139866044:139866066:[+] chr22:22127173:22127205:[-] nonBSJ supported CDS

circRNA 5':AGUC---------UUCCGGAUAAUU-UGGGUCU 3'


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target  3':CCAGCAUUAUGACGAGGUCUAUACCCACCCGGU 5'

 -20.60 2 RIC-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr22:22127173:22127205:[-] target 917746 chr22:22127175-22127176 T>C Intellectual_disability|Heart,_malformation_of|Abnormal_facial_shape|Specific_learning_disability|Atypical_behavior|Noonan_syndrome_13|not_provided ClinVar
chr22:22127173:22127205:[-] target 917745 chr22:22127176-22127177 C>T Intellectual_disability|Heart,_malformation_of|Abnormal_facial_shape|Specific_learning_disability|Atypical_behavior|Noonan_syndrome_13|not_provided ClinVar
chr22:22127173:22127205:[-] target 1804005 chr22:22127182-22127183 A>G Noonan_syndrome_13 ClinVar