Gene structure and interaction sites

 5'UTR

 CDS

 3'UTR

 Exon

 circRNA binding site

Detailed information
CircRNA interaction region Target interaction region Interaction type Target element RNA duplex MFE (kcal/mol) Reads Methods
chrX:139865824:139865872:[+] chr16:2814578:2814629:[+] nonBSJ supported Intron

circRNA 5': GGUCU---UCCAGUCAGUC-AGUGUCU-UCCAGAAAAAUCUACGUCUUCCACCA 3'


            |:||| |||||: || |||| |||||| |||| |||


target  3':CCUAGACAAAGGUCGACUAAUUCUUUGCCAGGUAAGUUUAGA---AGAAAUUGGA 5'

 -26.20 1 KARR-seq
chrX:139866680:139866698:[+] chr16:2813244:2813263:[+] nonBSJ supported CDS

circRNA 5':UCC-AGCAUCUCUGUGUCUU 3'


            || || || |||||


target  3':UGGAUCUACCCGAGACAGAC 5'

 -9.50 5 KARR-seq
chrX:139866683:139866712:[+] chr16:2813283:2813317:[+] nonBSJ supported CDS

circRNA 5':AGCAUCUCUGUGUCUUCCA---------GCAUCUUCAUG 3'


            || ||| |||||| || |||||:


target  3':CCGA--AGAAACAGAACCACUAUAAUAACG--GAAGUGA 5'

 -12.50 1 KARR-seq
chrX:139866680:139866699:[+] chr16:2813303:2813325:[+] nonBSJ supported CDS

circRNA 5':UCCAGCAU--C-UCUGUGUCUUC 3'


            |||| || | ||| ||||||


target  3':CGGUCUUACCGAAGAAACAGAAC 5'

 -11.20 1 KARR-seq
Variants map to interaction
Interaction region CircRNA/target Mutation ID Position Variant Associated trait Resource
chr16:2813283:2813317:[+] target 1333025 chr16:2813308-2813309 CAAAG>C Intellectual_developmental_disorder,_autosomal_dominant_72|Neurodevelopmental_disorder ClinVar
chr16:2813303:2813325:[+] target 1333025 chr16:2813308-2813309 CAAAG>C Intellectual_developmental_disorder,_autosomal_dominant_72|Neurodevelopmental_disorder ClinVar
chr16:2813283:2813317:[+] target - chr16:2813299-2813300 T>C LAML-KR ICGC